The Coalescent With Gene Conversion Carsten Wiuf

The Coalescent of Bacterial Populations

Gene Genealogies, Variation and Evolution - A Primer in Coalescent Theory

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A coalescence approach to gene conversion.

In this paper we develop a coalescent model with intralocus gene conversion. Such models are of increasing importance in the analysis of intralocus variability and linkage disequilibrium. We derive the distribution of the waiting time until a gene conversion event occurs in a sample in terms of the distribution of the length of the transferred segment, zeta. We do not assume any specific form o...

“ Integrative Analysis of the Genetic Factors behind Asthma and Atopic Dermatitis ” Part I : Previous Research Track Record

I moved to the Department of Statistics at Oxford University in September 2001, coming from Aarhus University, where I was director of BiRC (Bioinformatics Research Center). Since I have come to Oxford I have worked on a series of issues. Most of my work is focused on developing methodologies that can analyze data arising in molecular genetics and genomics with a comparative/evolutionary focus....

The genealogy, site frequency spectrum and ages of two nested mutant alleles.

In this paper we consider the genealogy of two nested mutant alleles, assuming the constant-size neutral coalescent model with infinite sites mutation. We study the conditional genealogy and derive explicit formulas for the joint and marginal site frequency spectra for the double, single and zero mutant allele. In addition, we find the mean ages of the two mutations. We show that the age of the...